


Hopefully the components of that volume of air will be clearer after reviewing the following illustrations. Difference in Anatomical and Physiological Dead Space. anatomic dead space + alveolar dead space. The part of (inhaled) tidal volume that cannot eliminate CO2. is more relevant to estimate physiologic dead space (also called Bohr dead space). Physiological Dead Space (VdCO2) The part of (inhaled) tidal volume that does not participate in gas exchange. And then real quick before we dive in: if you’re not familiar with the idea of dead space in general, it’s the concept that there is a difference between the quantity of air breathed in during a breath (tidal volume) and the volume of air that actually participates in gas exchange at the alveolar level (clinically relevant tidal volume). The gas volume of the conducting zone equals the anatomic dead space. Dead space is a concept that we generally discuss in the context of mechanical ventilation – this short series of graphics won’t get into too much detail on that, but we can point you towards our free book on the idea: The goal here is simply to review the different types of dead space, demonstrate them graphically, and point out specific interventions for each of the various types. The series of illustrations in this post demonstrate the different types of dead space encountered in clinical practice and interventions to address them. Alveolar dead space is the volume of alveoli that are ventilated but not perfused (or underperfused), and anatomical dead space is the volume of the respiratory system from the nose and mouth to the level of the distal airways at which gas exchange begins to take place.
